motilitAI: a machine learning framework for automatic prediction of human sperm motility

In this article, human semen samples from the Visem dataset are automatically assessed with machine learning methods for their quality with respect to sperm motility. Several regression models are trained to automatically predict the percentage (0–100) of progressive, non-progressive, and immotile spermatozoa. The videos are adopted for unsupervised tracking and two different feature extraction methods—in particular custom movement statistics and displacement features. We train multiple neural networks and support vector regression models on the extracted features. Best results are achieved using a linear Support Vector Regressor with an aggregated and quantized representation of individual displacement features of each sperm cell. Compared to the best submission of the Medico Multimedia for Medicine challenge, which used the same dataset and splits, the mean absolute error (MAE) could be reduced from 8.83 to 7.31. We provide the source code for our experiments on GitHub (Code available at: https://github.com/EIHW/motilitAI)

Zero-shot personalization of speech foundation models for depressed mood monitoring

The monitoring of depressed mood plays an important role as a diagnostic tool in psychotherapy. An automated analysis of speech can provide a non-invasive measurement of a patient’s affective state. While speech has been shown to be a useful biomarker for depression, existing approaches mostly build population-level models that aim to predict each individual’s diagnosis as a (mostly) static property. Because of inter-individual differences in symptomatology and mood regulation behaviors, these approaches are ill-suited to detect smaller temporal variations in depressed mood. We address this issue by introducing a zero-shot personalization of large speech foundation models. Compared with other personalization strategies, our work does not require labeled speech samples for enrollment. Instead, the approach makes use of adapters conditioned on subject-specific metadata. On a longitudinal dataset, we show that the method improves performance compared with a set of suitable baselines. Finally, applying our personalization strategy improves individual-level fairness

Distinguishing between pre- and post-treatment in the speech of patients with chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) causes lung inflammation and airflow blockage leading to a variety of respiratory symptoms; it is also a leading cause of death and affects millions of individuals around the world. Patients often require treatment and hospitalisation, while no cure is currently available. As COPD predominantly affects the respiratory system, speech and non-linguistic vocalisations present a major avenue for measuring the effect of treatment. In this work, we present results on a new COPD dataset of 20 patients, showing that, by employing personalisation through speaker-level feature normalisation, we can distinguish between pre- and post-treatment speech with an unweighted average recall (UAR) of up to 82\,\% in (nested) leave-one-speaker-out cross-validation. We further identify the most important features and link them to pathological voice properties, thus enabling an auditory interpretation of treatment effects. Monitoring tools based on such approaches may help objectivise the clinical status of COPD patients and facilitate personalised treatment plans.Comment: Accepted in INTERSPEECH 202

Distinguishing between pre- and post-treatment in the speech of patients with chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) causes lung inflammation and airflow blockage leading to a variety of respiratory symptoms; it is also a leading cause of death and affects millions of individuals around the world. Patients often require treatment and hospitalisation, while no cure is currently available. As COPD predominantly affects the respiratory system, speech and non-linguistic vocalisations present a major avenue for measuring the effect of treatment. In this work, we present results on a new COPD dataset of 20 patients, showing that, by employing personalisation through speaker-level feature normalisation, we can distinguish between pre- and post-treatment speech with an unweighted average recall (UAR) of up to 82% in (nested) leave-one-speaker-out cross-validation. We further identify the most important features and link them to pathological voice properties, thus enabling an auditory interpretation of treatment effects. Monitoring tools based on such approaches may help objectivise the clinical status of COPD patients and facilitate personalised treatment plans

The influence of pleasant and unpleasant odours on the acoustics of speech

Olfaction, i. e., the sense of smell is referred to as the ‘emotional sense’, as it has been shown to elicit affective responses. Yet, its influence on speech production has not been investigated. In this paper, we introduce a novel speech-based smell recognition approach, drawing from the fields of speech emotion recognition and personalised machine learning. In particular, we collected a corpus of 40 female speakers reading 2 short stories while either no scent, unpleasant odour (fish), or pleasant odour (peach) is applied through a nose clip. Further, we present a machine learning pipeline for the extraction of data representations, model training, and personalisation of the trained models. In a leave-one-speaker-out cross-validation, our best models trained on state-of-the-art wav2vec features achieve a classification rate of 68 % when distinguishing between speech produced under the influence of negative scent and no applied scent. In addition, we highlight the importance of personalisation approaches, showing that a speaker-based feature normalisation substantially improves performance across the evaluated experiments. In summary, the presented results indicate that odours have a weak, but measurable effect on the acoustics of speech

The ACM Multimedia 2023 Computational Paralinguistics Challenge: emotion share & requests

The ACM Multimedia 2023 Computational Paralinguistics Chal- lenge addresses two different problems for the first time in a re- search competition under well-defined conditions: In the Emotion Share Sub-Challenge, a regression on speech has to be made; and in the Requests Sub-Challenges, requests and complaints need to be de- tected. We describe the Sub-Challenges, baseline feature extraction, and classifiers based on the ‘usual’ ComParE features, the auDeep toolkit, and deep feature extraction from pre-trained CNNs using the DeepSpectrum toolkit; in addition, wav2vec2 models are used

Personalised depression forecasting using mobile sensor data and ecological momentary assessment

Introduction Digital health interventions are an effective way to treat depression, but it is still largely unclear how patients’ individual symptoms evolve dynamically during such treatments. Data-driven forecasts of depressive symptoms would allow to greatly improve the personalisation of treatments. In current forecasting approaches, models are often trained on an entire population, resulting in a general model that works overall, but does not translate well to each individual in clinically heterogeneous, real-world populations. Model fairness across patient subgroups is also frequently overlooked. Personalised models tailored to the individual patient may therefore be promising. Methods We investigate different personalisation strategies using transfer learning, subgroup models, as well as subject-dependent standardisation on a newly-collected, longitudinal dataset of depression patients undergoing treatment with a digital intervention (N=65 patients recruited). Both passive mobile sensor data as well as ecological momentary assessments were available for modelling. We evaluated the models’ ability to predict symptoms of depression (Patient Health Questionnaire-2; PHQ-2) at the end of each day, and to forecast symptoms of the next day. Results In our experiments, we achieve a best mean-absolute-error (MAE) of 0.801 (25% improvement) for predicting PHQ-2 values at the end of the day with subject-dependent standardisation compared to a non-personalised baseline (MAE=1.062). For one day ahead-forecasting, we can improve the baseline of 1.539 by 12% to a MAE of 1.349 using a transfer learning approach with shared common layers. In addition, personalisation leads to fairer models at group-level. Discussion Our results suggest that personalisation using subject-dependent standardisation and transfer learning can improve predictions and forecasts, respectively, of depressive symptoms in participants of a digital depression intervention. We discuss technical and clinical limitations of this approach, avenues for future investigations, and how personalised machine learning architectures may be implemented to improve existing digital interventions for depression

The ACM Multimedia 2022 Computational Paralinguistics Challenge: vocalisations, stuttering, activity, & mosquitoes

The ACM Multimedia 2022 Computational Paralinguistics Challenge addresses four different problems for the first time in a research competition under well-defined conditions: In the Vocalisations and Stuttering Sub-Challenges, a classification on human non-verbal vocalisations and speech has to be made; the Activity Sub-Challenge aims at beyond-audio human activity recognition from smartwatch sensor data; and in the Mosquitoes Sub-Challenge, mosquitoes need to be detected. We describe the Sub-Challenges, baseline feature extraction, and classifiers based on the 'usual' ComParE and BoAW features, the auDeep toolkit, and deep feature extraction from pre-trained CNNs using the DeepSpectrum toolkit; in addition, we add end-to-end sequential modelling, and a log-mel-128-BNN